Therapeutic Target in Human Hepatocellular Carcinoma Definition of Ubiquitination Modulator COP1 as a Novel
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منابع مشابه
rapeutic Target in Human Hepatocellular Carcinoma
Downlo development of targeted therapeutics for hepatocellular carcinoma (HCC) remains a major challenge. iquitination modulator COP1 regulates p53 activity by ubiquitination and it is frequently overexpressed an HCC. In this study, we tested the hypothesis that COP1 blockade by short interfering RNA (siRNA)– ted inhibition could affect the course of HCC progression. The COP1 isoform COP1-1 was...
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تاریخ انتشار 2010